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Introduction: Breast cancer is one of the important disease responsible for the death of women, both in Serbia and in the world. The incidence of breast cancer in Serbia is 20, 2%, from all leading cancer sites in females (data obtained from Cancer Registry of Serbia 2015). In 2008 Serbia had the highest mortality rate from breast cancer (ASR-W 2008: 22.7/100,000), among all European countries. Case report: Patient M.T. P3 G3, 37 years old with invasive ductal cancer of the right breast (treated from 2012 till 2016), the moderately differentiated histological type with present lymphovascular and perineural invasion of pTT1, HG2, pN2, receptor status ER 7, PR 8, HER2 0, Ki-67 30% tumor cells, admitted to the Gynecology Department because the NMR recording of small pelvis confirmed pregnancy in the uterus. This recording was done because doubts on metastatic change on segment LS on the spine. Last period was in 2012. The interval of birth between this and the last pregnancy was 15 years. On the gynecological ultrasound was diagnosed a live normal fetus, the crown-rump length (CRL) was 74mm, (13 weeks and 4 days). Nuchal translucency was 1, 6mm, and the values of Free-Beta HCG-2,53 MoM, PAPP-A 0,7 MoM. The pregnancy has come from the natural cycle. The amniocentesis is recommended and the result shows a normal XX karyotype of the fetus. The pregnancy was developed normally, the baby was born in 35-36 weeks (13.02.2018) of gestation with cesarean section because of previous two cesarean section of mother. The female neonatus has body mass 2390g/48 cm, AS 8/9. Postoperation decurzus was normally. The metastatic change was not confirmed during pregnancy and after the delivery. Discussion: In the literature, cases of natural pregnancy after the treatment of breast cancer are rarely described. Conclusion: The patient M.T. was the first patient with treated breast cancer who delivery in our Hospital. Reference: 1. Ilic M and Ilic I (2018) Cancer mortality in Serbia, 1991–2015: an age-period-cohort and joinpoint regression analysis. Cancer Communications 38(1): 10.